研究成果・広報活動
研究成果一覧
学術論文 2022年
Genetic diversity fuels gene discovery for tobacco and alcohol use.
Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Choquet H, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Esko T, Faul JD, Silva LF, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gieger C, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung YJ, Hunter DJ, Hveem K, Hwang SJ, Hwu CM, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Kardia SLR, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee WJ, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, Mägi R, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medland SE, Metspalu A, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Orrù V, Palmer ND, Palviainen T, Pandit A, Park SL, Peters U, Peters A, Peyser PA, Polderman TJC, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Zöllner S, Zuccolo L; 23andMe Research Team; Biobank Japan Project; Batini C, Bergen AW, Bierut LJ, David SP, Gagliano Taliun SA, Hancock DB, Jiang B, Munafò MR, Thorgeirsson TE, Liu DJ, Vrieze S.
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
Aragam KG, Jiang T, Goel A, Kanoni S, Wolford BN, Atri DS, Weeks EM, Wang M, Hindy G, Zhou W, Grace C, Roselli C, Marston NA, Kamanu FK, Surakka I, Venegas LM, Sherliker P, Koyama S, Ishigaki K, Åsvold BO, Brown MR, Brumpton B, de Vries PS, Giannakopoulou O, Giardoglou P, Gudbjartsson DF, Güldener U, Haider SMI, Helgadottir A, Ibrahim M, Kastrati A, Kessler T, Kyriakou T, Konopka T, Li L, Ma L, Meitinger T, Mucha S, Munz M, Murgia F, Nielsen JB, Nöthen MM, Pang S, Reinberger T, Schnitzler G, Smedley D, Thorleifsson G, von Scheidt M, Ulirsch JC; Biobank Japan; EPIC-CVD, Arnar DO, Burtt NP, Costanzo MC, Flannick J, Ito K, Jang DK, Kamatani Y, Khera AV, Komuro I, Kullo IJ, Lotta LA, Nelson CP, Roberts R, Thorgeirsson G, Thorsteinsdottir U, Webb TR, Baras A, Björkegren JLM, Boerwinkle E, Dedoussis G, Holm H, Hveem K, Melander O, Morrison AC, Orho-Melander M, Rallidis LS, Ruusalepp A, Sabatine MS, Stefansson K, Zalloua P, Ellinor PT, Farrall M, Danesh J, Ruff CT, Finucane HK, Hopewell JC, Clarke R, Gupta RM, Erdmann J, Samani NJ, Schunkert H, Watkins H, Willer CJ, Deloukas P, Kathiresan S, Butterworth AS; CARDIoGRAMplusC4D Consortium.
Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population
Hanyuda A, Goto A, Nakatochi M, Sutoh Y, Narita A, Nakano S, Katagiri R, Wakai K, Takashima N, Koyama T, Arisawa K, Imoto I, Momozawa Y, Tanno K, Shimizu A, Hozawa A, Kinoshita K, Yamaji T, Sawada N, Iwagami M, Yuki K, Tsubota K, Negishi K, Matsuo K, Yamamoto M, Sasaki M, Tsugane S, Iwasaki M.
Genetic Architectures Underlie Onset Age of Atopic Dermatitis
Keiko Hikino, Nao Tanaka, Masaru Koido, Kohei Tomizuka, Yoshinao Koike, Shuji Ito, Akari Suzuki, Yukihide Momozawa, Yoichiro Kamatani, BioBank Japan Project Consortium; Taisei Mushiroda, Chikashi Terao
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Børte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li L, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-Moret NC, Ovbiagele B, Peters A, Psaty BM, Rich SS, Rosand J, Sabatine MS, Sacco RL, Saleheen D, Sandset EC, Salomaa V, Sargurupremraj M, Sasaki M, Satizabal CL, Schmidt CO, Shimizu A, Smith NL, Sloane KL, Sutoh Y, Sun YV, Tanno K, Tiedt S, Tatlisumak T, Torres-Aguila NP, Tiwari HK, Trégouët DA, Trompet S, Tuladhar AM, Tybjærg-Hansen A, van Vugt M, Vibo R, Verma SS, Wiggins KL, Wennberg P, Woo D, Wilson PWF, Xu H, Yang Q, Yoon K; COMPASS Consortium; INVENT Consortium; Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group; Estonian Biobank; PRECISE4Q Consortium; FinnGen Consortium; NINDS Stroke Genetics Network (SiGN); MEGASTROKE Consortium; SIREN Consortium; China Kadoorie Biobank Collaborative Group; VA Million Veteran Program; International Stroke Genetics Consortium (ISGC); Biobank Japan; CHARGE Consortium; GIGASTROKE Consortium, Millwood IY, Gieger C, Ninomiya T, Grabe HJ, Jukema JW, Rissanen IL, Strbian D, Kim YJ, Chen PH, Mayerhofer E, Howson JMM, Irvin MR, Adams H, Wassertheil-Smoller S, Christensen K, Ikram MA, Rundek T, Worrall BB, Lathrop GM, Riaz M, Simonsick EM, Kõrv J, França PHC, Zand R, Prasad K, Frikke-Schmidt R, de Leeuw FE, Liman T, Haeusler KG, Ruigrok YM, Heuschmann PU, Longstreth WT, Jung KJ, Bastarache L, Paré G, Damrauer SM, Chasman DI, Rotter JI, Anderson CD, Zwart JA, Niiranen TJ, Fornage M, Liaw YP, Seshadri S, Fernández-Cadenas I, Walters RG, Ruff CT, Owolabi MO, Huffman JE, Milani L, Kamatani Y, Dichgans M, Debette S.
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis
Kazuyoshi Ishigaki, Saori Sakaue, Chikashi Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, Tiffany Amariuta, Chun Lai Too, Vincent A. Laufer, Ian C. Scott, Sebastien Viatte, Meiko Takahashi, Koichiro Ohmura, Akira Murasawa, Motomu Hashimoto, Hiromu Ito, Mohammed Hammoudeh, Samar Al Emadi, Basel K. Masri, Hussein Halabi, Humeira Badsha, Imad W. Uthman, Xin Wu, Li Lin, Ting Li, Darren Plant, Anne Barton, Gisela Orozco, Suzanne M. M. Verstappen, John Bowes, Alexander J. MacGregor, Suguru Honda, Masaru Koido, Kohei Tomizuka, Yoichiro Kamatani, Hiroaki Tanaka, Eiichi Tanaka, Akari Suzuki, Yuichi Maeda, Kenichi Yamamoto, Satoru Miyawaki, Gang Xie, Jinyi Zhang, Christopher I. Amos, Ed Keystone, Gertjan Wolbink, Irene van der Horst-Bruinsma, Jing Cui, Katherine P. Liao, Robert J. Carroll, Hye-Soon Lee, So-Young Bang, Katherine A. Siminovitch, Niek de Vries, Lars Alfredsson, Solbritt Rantapää-Dahlqvist, Elizabeth W. Karlson, Sang-Cheol Bae, Robert P. Kimberly, Jeffrey C. Edberg, Xavier Mariette, Tom Huizinga, Philippe Dieudé, Matthias Schneider, Martin Kerick, Joshua C. Denny, The Biobank Japan Project, Koichi Matsuda, Keitaro Matsuo, Tsuneyo Mimori, Fumihiko Matsuda, Keishi Fujio, Yoshiya Tanaka, Atsushi Kumanogoh, Matthew Traylor, Cathryn M. Lewis, Stephen Eyre, Huji Xu, Richa Saxena, Thurayya Arayssi, Yuta Kochi, Katsunori Ikari, Masayoshi Harigai, Peter K. Gregersen, Kazuhiko Yamamoto, S. Louis Bridges, Jr, Leonid Padyukov, Javier Martin, Lars Klareskog, Yukinori Okada and Soumya Raychaudhuri
Association between germline pathogenic variants in cancer-predisposing genes and lymphoma risk
Yoshiaki Usui, Yusuke Iwasaki, Keitaro Matsuo, Mikiko Endo, Yoichiro Kamatani, Makoto Hirata, Kokichi Sugano, Teruhiko Yoshida, Koichi Matsuda, Yoshinori Murakami, Yoshinobu Maeda, Hidewaki Nakagawa, Yukihide Momozawa
Population-based Screening for Hereditary Colorectal Cancer Variants in Japan
Masashi Fujita, Xiaoxi Liu, Yusuke Iwasaki, Chikashi Terao, Keijiro Mizukami, Eiryo Kawakami, Sadaaki Takata, Chihiro Inai, Tomomi Aoi, Misaki Mizukoshi, Kazuhiro Maejima, Makoto Hirata, Yoshinori Murakami, Yoichiro Kamatani, Michiaki Kubo, Kiwamu Akagi, Koichi Matsuda, Hidewaki Nakagawa, and Yukihide Momozawa
Stroke genetics informs drug discovery and risk prediction across ancestries
Aniket Mishra , Rainer Malik , Tsuyoshi Hachiya , Tuuli Jürgenson , Shinichi Namba , Daniel C Posner , Frederick K Kamanu , Masaru Koido , Quentin Le Grand , Mingyang Shi , Yunye He , Marios K Georgakis , Ilana Caro , Kristi Krebs , Yi-Ching Liaw , Felix C Vaura , Kuang Lin , Bendik Slagsvold Winsvold , Vinodh Srinivasasainagendra , Livia Parodi , Hee-Joon Bae , Ganesh Chauhan , Michael R Chong , Liisa Tomppo , Rufus Akinyemi , Gennady V Roshchupkin , Naomi Habib , Yon Ho Jee , Jesper Qvist Thomassen , Vida Abedi , Jara Cárcel-Márquez , Marianne Nygaard , Hampton L Leonard , Chaojie Yang , Ekaterina Yonova-Doing , Maria J Knol , Adam J Lewis , Renae L Judy , Tetsuro Ago , Philippe Amouyel , Nicole D Armstrong , Mark K Bakker , Traci M Bartz , David A Bennett , Joshua C Bis , Constance Bordes , Sigrid Børte , Anael Cain , Paul M Ridker , Kelly Cho , Zhengming Chen , Carlos Cruchaga , John W Cole , Phil L de Jager , Rafael de Cid , Matthias Endres , Leslie E Ferreira , Mirjam I Geerlings , Natalie C Gasca , Vilmundur Gudnason , Jun Hata , Jing He , Alicia K Heath , Yuk-Lam Ho , Aki S Havulinna , Jemma C Hopewell , Hyacinth I Hyacinth , Michael Inouye , Mina A Jacob , Christina E Jeon , Christina Jern , Masahiro Kamouchi , Keith L Keene , Takanari Kitazono , Steven J Kittner , Takahiro Konuma , Amit Kumar , Paul Lacaze , Lenore J Launer , Keon-Joo Lee , Kaido Lepik , Jiang Li , Liming Li , Ani Manichaikul , Hugh S Markus , Nicholas A Marston , Thomas Meitinger , Braxton D Mitchell , Felipe A Montellano , Takayuki Morisaki , Thomas H Mosley , Mike A Nalls , Børge G Nordestgaard , Martin J O'Donnell , Yukinori Okada , N Charlotte Onland-Moret , Bruce Ovbiagele , Annette Peters , Bruce M Psaty , Stephen S Rich , Jonathan Rosand , Marc S Sabatine , Ralph L Sacco , Danish Saleheen , Else Charlotte Sandset , Veikko Salomaa , Muralidharan Sargurupremraj , Makoto Sasaki , Claudia L Satizabal , Carsten O Schmidt , Atsushi Shimizu , Nicholas L Smith , Kelly L Sloane , Yoichi Sutoh , Yan V Sun , Kozo Tanno , Steffen Tiedt , Turgut Tatlisumak , Nuria P Torres-Aguila , Hemant K Tiwari , David-Alexandre Trégouët , Stella Trompet , Anil Man Tuladhar , Anne Tybjærg-Hansen , Marion van Vugt , Riina Vibo , Shefali S Verma , Kerri L Wiggins , Patrik Wennberg , Daniel Woo , Peter W F Wilson , Huichun Xu , Qiong Yang , Kyungheon Yoon , COMPASS Consortium; INVENT Consortium; Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group; Estonian Biobank; PRECISEQ Consortium; FinnGen Consortium; NINDS Stroke Genetics Network (SiGN); MEGASTROKE Consortium; SIREN Consortium; China Kadoorie Biobank Collaborative Group; VA Million Veteran Program; International Stroke Genetics Consortium (ISGC); Biobank Japan; CHARGE Consortium; GIGASTROKE Consortium; Iona Y Millwood , Christian Gieger , Toshiharu Ninomiya , Hans J Grabe , J Wouter Jukema , Ina L Rissanen , Daniel Strbian , Young Jin Kim , Pei-Hsin Chen , Ernst Mayerhofer , Joanna M M Howson , Marguerite R Irvin , Hieab Adams , Sylvia Wassertheil-Smoller , Kaare Christensen , Mohammad A Ikram , Tatjana Rundek , Bradford B Worrall , G Mark Lathrop , Moeen Riaz , Eleanor M Simonsick , Janika Kõrv , Paulo H C França , Ramin Zand , Kameshwar Prasad , Ruth Frikke-Schmidt , Frank-Erik de Leeuw , Thomas Liman , Karl Georg Haeusler , Ynte M Ruigrok , Peter Ulrich Heuschmann , W T Longstreth , Keum Ji Jung , Lisa Bastarache , Guillaume Paré , Scott M Damrauer , Daniel I Chasman , Jerome I Rotter , Christopher D Anderson , John-Anker Zwart , Teemu J Niiranen , Myriam Fornage , Yung-Po Liaw , Sudha Seshadri , Israel Fernández-Cadenas , Robin G Walters , Christian T Ruff , Mayowa O Owolabi , Jennifer E Huffman , Lili Milani , Yoichiro Kamatani , Martin Dichgans , Stephanie Debette Collaborators, Affiliations expand
Genetic footprints of assortative mating in the Japanese population
Kenichi Yamamoto, Kyuto Sonehara, Shinichi Namba, Takahiro Konuma, Hironori Masuko, Satoru Miyawaki, The BioBank Japan Project, Yoichiro Kamatani, Nobuyuki Hizawa, Keiichi Ozono, Loic Yengo & Yukinori Okada
DOCK2 is involved in the host genetics and biology of severe COVID-19
Ho Namkoong # , Ryuya Edahiro # , Tomomi Takano , Hiroshi Nishihara , Yuya Shirai , Kyuto Sonehara , Hiromu Tanaka , Shuhei Azekawa , Yohei Mikami , Ho Lee , Takanori Hasegawa , Koji Okudela , Daisuke Okuzaki , Daisuke Motooka , Masahiro Kanai , Tatsuhiko Naito , Kenichi Yamamoto , Qingbo S Wang , Ryunosuke Saiki , Rino Ishihara , Yuta Matsubara , Junko Hamamoto , Hiroyuki Hayashi , Yukihiro Yoshimura , Natsuo Tachikawa , Emmy Yanagita , Takayoshi Hyugaji , Eigo Shimizu , Kotoe Katayama , Yasuhiro Kato , Takayoshi Morita , Kazuhisa Takahashi , Norihiro Harada , Toshio Naito , Makoto Hiki , Yasushi Matsushita , Haruhi Takagi , Ryousuke Aoki , Ai Nakamura , Sonoko Harada , Hitoshi Sasano , Hiroki Kabata , Katsunori Masaki , Hirofumi Kamata , Shinnosuke Ikemura , Shotaro Chubachi , Satoshi Okamori , Hideki Terai , Atsuho Morita , Takanori Asakura , Junichi Sasaki , Hiroshi Morisaki , Yoshifumi Uwamino , Kosaku Nanki , Sho Uchida , Shunsuke Uno , Tomoyasu Nishimura , Takashi Ishiguro , Taisuke Isono , Shun Shibata , Yuma Matsui , Chiaki Hosoda , Kenji Takano , Takashi Nishida , Yoichi Kobayashi , Yotaro Takaku , Noboru Takayanagi , Soichiro Ueda , Ai Tada , Masayoshi Miyawaki , Masaomi Yamamoto , Eriko Yoshida , Reina Hayashi , Tomoki Nagasaka , Sawako Arai , Yutaro Kaneko , Kana Sasaki , Etsuko Tagaya , Masatoshi Kawana , Ken Arimura , Kunihiko Takahashi , Tatsuhiko Anzai , Satoshi Ito , Akifumi Endo , Yuji Uchimura , Yasunari Miyazaki , Takayuki Honda , Tomoya Tateishi , Shuji Tohda , Naoya Ichimura , Kazunari Sonobe , Chihiro Tani Sassa , Jun Nakajima , Yasushi Nakano , Yukiko Nakajima , Ryusuke Anan , Ryosuke Arai , Yuko Kurihara , Yuko Harada , Kazumi Nishio , Tetsuya Ueda , Masanori Azuma , Ryuichi Saito , Toshikatsu Sado , Yoshimune Miyazaki , Ryuichi Sato , Yuki Haruta , Tadao Nagasaki , Yoshinori Yasui , Yoshinori Hasegawa , Yoshikazu Mutoh , Tomoki Kimura , Tomonori Sato , Reoto Takei , Satoshi Hagimoto , Yoichiro Noguchi , Yasuhiko Yamano , Hajime Sasano , Sho Ota , Yasushi Nakamori , Kazuhisa Yoshiya , Fukuki Saito , Tomoyuki Yoshihara , Daiki Wada , Hiromu Iwamura , Syuji Kanayama , Shuhei Maruyama , Takashi Yoshiyama , Ken Ohta , Hiroyuki Kokuto , Hideo Ogata , Yoshiaki Tanaka , Kenichi Arakawa , Masafumi Shimoda , Takeshi Osawa , Hiroki Tateno , Isano Hase , Shuichi Yoshida , Shoji Suzuki , Miki Kawada , Hirohisa Horinouchi , Fumitake Saito , Keiko Mitamura , Masao Hagihara , Junichi Ochi , Tomoyuki Uchida , Rie Baba , Daisuke Arai , Takayuki Ogura , Hidenori Takahashi , Shigehiro Hagiwara , Genta Nagao , Shunichiro Konishi , Ichiro Nakachi , Koji Murakami , Mitsuhiro Yamada , Hisatoshi Sugiura , Hirohito Sano , Shuichiro Matsumoto , Nozomu Kimura , Yoshinao Ono , Hiroaki Baba , Yusuke Suzuki , Sohei Nakayama , Keita Masuzawa , Shinichi Namba , Ken Suzuki , Yoko Naito , Yu-Chen Liu , Ayako Takuwa , Fuminori Sugihara , James B Wing , Shuhei Sakakibara , Nobuyuki Hizawa , Takayuki Shiroyama , Satoru Miyawaki , Yusuke Kawamura , Akiyoshi Nakayama , Hirotaka Matsuo , Yuichi Maeda , Takuro Nii , Yoshimi Noda , Takayuki Niitsu , Yuichi Adachi , Takatoshi Enomoto , Saori Amiya , Reina Hara , Yuta Yamaguchi , Teruaki Murakami , Tomoki Kuge , Kinnosuke Matsumoto , Yuji Yamamoto , Makoto Yamamoto , Midori Yoneda , Toshihiro Kishikawa , Shuhei Yamada , Shuhei Kawabata , Noriyuki Kijima , Masatoshi Takagaki , Noah Sasa , Yuya Ueno , Motoyuki Suzuki , Norihiko Takemoto , Hirotaka Eguchi , Takahito Fukusumi , Takao Imai , Munehisa Fukushima , Haruhiko Kishima , Hidenori Inohara , Kazunori Tomono , Kazuto Kato , Meiko Takahashi , Fumihiko Matsuda , Haruhiko Hirata , Yoshito Takeda , Hidefumi Koh , Tadashi Manabe , Yohei Funatsu , Fumimaro Ito , Takahiro Fukui , Keisuke Shinozuka , Sumiko Kohashi , Masatoshi Miyazaki , Tomohisa Shoko , Mitsuaki Kojima , Tomohiro Adachi , Motonao Ishikawa , Kenichiro Takahashi , Takashi Inoue , Toshiyuki Hirano , Keigo Kobayashi , Hatsuyo Takaoka , Kazuyoshi Watanabe , Naoki Miyazawa , Yasuhiro Kimura , Reiko Sado , Hideyasu Sugimoto , Akane Kamiya , Naota Kuwahara , Akiko Fujiwara , Tomohiro Matsunaga , Yoko Sato , Takenori Okada , Yoshihiro Hirai , Hidetoshi Kawashima , Atsuya Narita , Kazuki Niwa , Yoshiyuki Sekikawa , Koichi Nishi , Masaru Nishitsuji , Mayuko Tani , Junya Suzuki , Hiroki Nakatsumi , Takashi Ogura , Hideya Kitamura , Eri Hagiwara , Kota Murohashi , Hiroko Okabayashi , Takao Mochimaru , Shigenari Nukaga , Ryosuke Satomi , Yoshitaka Oyamada , Nobuaki Mori , Tomoya Baba , Yasutaka Fukui , Mitsuru Odate , Shuko Mashimo , Yasushi Makino , Kazuma Yagi , Mizuha Hashiguchi , Junko Kagyo , Tetsuya Shiomi , Satoshi Fuke , Hiroshi Saito , Tomoya Tsuchida , Shigeki Fujitani , Mumon Takita , Daiki Morikawa , Toru Yoshida , Takehiro Izumo , Minoru Inomata , Naoyuki Kuse , Nobuyasu Awano , Mari Tone , Akihiro Ito , Yoshihiko Nakamura , Kota Hoshino , Junichi Maruyama , Hiroyasu Ishikura , Tohru Takata , Toshio Odani , Masaru Amishima , Takeshi Hattori , Yasuo Shichinohe , Takashi Kagaya , Toshiyuki Kita , Kazuhide Ohta , Satoru Sakagami , Kiyoshi Koshida , Kentaro Hayashi , Tetsuo Shimizu , Yutaka Kozu , Hisato Hiranuma , Yasuhiro Gon , Namiki Izumi , Kaoru Nagata , Ken Ueda , Reiko Taki , Satoko Hanada , Kodai Kawamura , Kazuya Ichikado , Kenta Nishiyama , Hiroyuki Muranaka , Kazunori Nakamura , Naozumi Hashimoto , Keiko Wakahara , Koji Sakamoto , Norihito Omote , Akira Ando , Nobuhiro Kodama , Yasunari Kaneyama , Shunsuke Maeda , Takashige Kuraki , Takemasa Matsumoto , Koutaro Yokote , Taka-Aki Nakada , Ryuzo Abe , Taku Oshima , Tadanaga Shimada , Masahiro Harada , Takeshi Takahashi , Hiroshi Ono , Toshihiro Sakurai , Takayuki Shibusawa , Yoshifumi Kimizuka , Akihiko Kawana , Tomoya Sano , Chie Watanabe , Ryohei Suematsu , Hisako Sageshima , Ayumi Yoshifuji , Kazuto Ito , Saeko Takahashi , Kota Ishioka , Morio Nakamura , Makoto Masuda , Aya Wakabayashi , Hiroki Watanabe , Suguru Ueda , Masanori Nishikawa , Yusuke Chihara , Mayumi Takeuchi , Keisuke Onoi , Jun Shinozuka , Atsushi Sueyoshi , Yoji Nagasaki , Masaki Okamoto , Sayoko Ishihara , Masatoshi Shimo , Yoshihisa Tokunaga , Yu Kusaka , Takehiko Ohba , Susumu Isogai , Aki Ogawa , Takuya Inoue , Satoru Fukuyama , Yoshihiro Eriguchi , Akiko Yonekawa , Keiko Kan-O , Koichiro Matsumoto , Kensuke Kanaoka , Shoichi Ihara , Kiyoshi Komuta , Yoshiaki Inoue , Shigeru Chiba , Kunihiro Yamagata , Yuji Hiramatsu , Hirayasu Kai , Koichiro Asano , Tsuyoshi Oguma , Yoko Ito , Satoru Hashimoto , Masaki Yamasaki , Yu Kasamatsu , Yuko Komase , Naoya Hida , Takahiro Tsuburai , Baku Oyama , Minoru Takada , Hidenori Kanda , Yuichiro Kitagawa , Tetsuya Fukuta , Takahito Miyake , Shozo Yoshida , Shinji Ogura , Shinji Abe , Yuta Kono , Yuki Togashi , Hiroyuki Takoi , Ryota Kikuchi , Shinichi Ogawa , Tomouki Ogata , Shoichiro Ishihara , Arihiko Kanehiro , Shinji Ozaki , Yasuko Fuchimoto , Sae Wada , Nobukazu Fujimoto , Kei Nishiyama , Mariko Terashima , Satoru Beppu , Kosuke Yoshida , Osamu Narumoto , Hideaki Nagai , Nobuharu Ooshima , Mitsuru Motegi , Akira Umeda , Kazuya Miyagawa , Hisato Shimada , Mayu Endo , Yoshiyuki Ohira , Masafumi Watanabe , Sumito Inoue , Akira Igarashi , Masamichi Sato , Hironori Sagara , Akihiko Tanaka , Shin Ohta , Tomoyuki Kimura , Yoko Shibata , Yoshinori Tanino , Takefumi Nikaido , Hiroyuki Minemura , Yuki Sato , Yuichiro Yamada , Takuya Hashino , Masato Shinoki , Hajime Iwagoe , Hiroshi Takahashi , Kazuhiko Fujii , Hiroto Kishi , Masayuki Kanai , Tomonori Imamura , Tatsuya Yamashita , Masakiyo Yatomi , Toshitaka Maeno , Shinichi Hayashi , Mai Takahashi , Mizuki Kuramochi , Isamu Kamimaki , Yoshiteru Tominaga , Tomoo Ishii , Mitsuyoshi Utsugi , Akihiro Ono , Toru Tanaka , Takeru Kashiwada , Kazue Fujita , Yoshinobu Saito , Masahiro Seike , Hiroko Watanabe , Hiroto Matsuse , Norio Kodaka , Chihiro Nakano , Takeshi Oshio , Takatomo Hirouchi , Shohei Makino , Moritoki Egi , Biobank Japan Project; Yosuke Omae , Yasuhito Nannya , Takafumi Ueno , Kazuhiko Katayama , Masumi Ai , Yoshinori Fukui , Atsushi Kumanogoh , Toshiro Sato , Naoki Hasegawa , Katsushi Tokunaga , Makoto Ishii , Ryuji Koike , Yuko Kitagawa , Akinori Kimura , Seiya Imoto , Satoru Miyano , Seishi Ogawa , Takanori Kanai , Koichi Fukunaga , Yukinori Okada
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.
Tcheandjieu C, Zhu X, Hilliard AT, Clarke SL, Napolioni V, Ma S, Lee KM, Fang H, Chen F, Lu Y, Tsao NL, Raghavan S, Koyama S, Gorman BR, Vujkovic M, Klarin D, Levin MG, Sinnott-Armstrong N, Wojcik GL, Plomondon ME, Maddox TM, Waldo SW, Bick AG, Pyarajan S, Huang J, Song R, Ho YL, Buyske S, Kooperberg C, Haessler J, Loos RJF, Do R, Verbanck M, Chaudhary K, North KE, Avery CL, Graff M, Haiman CA, Le Marchand L, Wilkens LR, Bis JC, Leonard H, Shen B, Lange LA, Giri A, Dikilitas O, Kullo IJ, Stanaway IB, Jarvik GP, Gordon AS, Hebbring S, Namjou B, Kaufman KM, Ito K, Ishigaki K, Kamatani Y, Verma SS, Ritchie MD, Kember RL, Baras A, Lotta LA, Kathiresan S, Hauser ER, Miller DR, Lee JS, Saleheen D, Reaven PD, Cho K, Gaziano JM, Natarajan P, Huffman JE, Voight BF, Rader DJ, Chang KM, Lynch JA, Damrauer SM, Wilson PWF, Tang H, Sun YV, Tsao PS, O'Donnell CJ, Assimes TL
Genetic analysis of right heart structure and function in 40,000 people
James P Pirruccello , Paolo Di Achille , Victor Nauffal , Mahan Nekoui , Samuel F Friedman , Marcus D R Klarqvist , Mark D Chaffin , Lu-Chen Weng , Jonathan W Cunningham , Shaan Khurshid , Carolina Roselli , Honghuang Lin , Satoshi Koyama , Kaoru Ito , Yoichiro Kamatani , Issei Komuro , BioBank Japan Project; Sean J Jurgens , Emelia J Benjamin , Puneet Batra , Pradeep Natarajan , Kenney Ng , Udo Hoffmann , Steven A Lubitz , Jennifer E Ho , Mark E Lindsay , Anthony A Philippakis , Patrick T Ellinor
Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians
Jie Ping,Yaohua Yang,Wanqing Wen,Sun-Seog Kweon,Koichi Matsuda,Wei-Hua Jia,Aesun Shin,Yu-Tang Gao,Keitaro Matsuo,Jeongseon Kim,Dong-Hyun Kim,Sun Ha Jee,Qiuyin Cai,Zhishan Chen,Ran Tao,Min-Ho Shin,Chizu Tanikawa,Zhi-Zhong Pan,Jae Hwan Oh,Isao Oze,Yoon-Ok Ahn,Keum Ji Jung,Zefang Ren,Xiao-Ou Shu,Jirong Long,Wei Zheng
Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component
Shirai Y, Nakanishi Y, Suzuki A, Konaka H, Nishikawa R, Sonehara K, Namba S, Tanaka H, Masuda T, Yaga M, Satoh S, Izumi M, Mizuno Y, Jo T, Maeda Y, Nii T, Oguro-Igashira E; Biobank Japan Project, Morisaki T, Kamatani Y, Nakayamada S, Nishigori C, Tanaka Y, Takeda Y, Yamamoto K, Kumanogoh A, Okada Y.
Association of germline TYK2 variation with lung cancer and non-Hodgkin lymphoma risk
James Yarmolinsky , Christopher I Amos , Rayjean J Hung , Victor Moreno , Kimberley Burrows , Karl Smith-Byrne , Joshua R Atkins , Paul Brennan , Colon Cancer Family Registry (CCFR), Colorectal Cancer Transdisciplinary study (CORECT), Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome (PRACTICAL) consortium; James D McKay , Richard M Martin , George Davey Smith
Different risk genes contribute to clear cell and non-clear cell renal cell carcinoma in 1532 Japanese patients and 5996 controls
Yuya Sekine , Yusuke Iwasaki , Tomomi Aoi , Mikiko Endo , Makoto Hirata , Yoichiro Kamatani , Koichi Matsuda , Kokichi Sugano , Teruhiko Yoshida , Yoshinori Murakami , Tomohiro Fukui , Shusuke Akamatsu , Osamu Ogawa , Hidewaki Nakagawa , Kazuyuki Numakura , Shintaro Narita , Tomonori Habuchi , Yukihide Momozawa
Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study
Shogo Dofuku, Kyuto Sonehara, Satoru Miyawaki, Saori Sakaue, Hideaki Imai, Masahiro Shimizu, Hiroki Hongo, Yuki Shinya, Kenta Ohara, Yu Teranishi, Atsushi Okano, Hideaki Ono, Hirofumi Nakatomi, Akira Teraoka, Kenichi Yamamoto, Yuichi Maeda, Takuro Nii, Toshihiro Kishikawa, Ken Suzuki, Jun Hirata, Meiko Takahashi, Koichi Matsuda, Atsushi Kumanogoh, Fumihiko Matsuda, Yukinori Okada & Nobuhito Saito
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals
Winkler TW, Rasheed H, Teumer A, Gorski M, Rowan BX, Stanzick KJ, Thomas LF, Tin A, Hoppmann A, Chu AY, Tayo B, Thio CHL, Cusi D, Chai JF, Sieber KB, Horn K, Li M, Scholz M, Cocca M, Wuttke M, van der Most PJ, Yang Q, Ghasemi S, Nutile T, Li Y, Pontali G, Günther F, Dehghan A, Correa A, Parsa A, Feresin A, de Vries APJ, Zonderman AB, Smith AV, Oldehinkel AJ, De Grandi A, Rosenkranz AR, Franke A, Teren A, Metspalu A, Hicks AA, Morris AP, Tönjes A, Morgan A, Podgornaia AI, Peters A, Körner A, Mahajan A, Campbell A, Freedman BI, Spedicati B, Ponte B, Schöttker B, Brumpton B, Banas B, Krämer BK, Jung B, Åsvold BO, Smith BH, Ning B, Penninx BWJH, Vanderwerff BR, Psaty BM, Kammerer CM, Langefeld CD, Hayward C, Spracklen CN, Robinson-Cohen C, Hartman CA, Lindgren CM, Wang C, Sabanayagam C, Heng CK, Lanzani C, Khor CC, Cheng CY, Fuchsberger C, Gieger C, Shaffer CM, Schulz CA, Willer CJ, Chasman DI, Gudbjartsson DF, Ruggiero D, Toniolo D, Czamara D, Porteous DJ, Waterworth DM, Mascalzoni D, Mook-Kanamori DO, Reilly DF, Daw EW, Hofer E, Boerwinkle E, Salvi E, Bottinger EP, Tai ES, Catamo E, Rizzi F, Guo F, Rivadeneira F, Guilianini F, Sveinbjornsson G, Ehret G, Waeber G, Biino G, Girotto G, Pistis G, Nadkarni GN, Delgado GE, Montgomery GW, Snieder H, Campbell H, White HD, Gao H, Stringham HM, Schmidt H, Li H, Brenner H, Holm H, Kirsten H, Kramer H, Rudan I, Nolte IM, Tzoulaki I, Olafsson I, Martins J, Cook JP, Wilson JF, Halbritter J, Felix JF, Divers J, Kooner JS, Lee JJ, O'Connell J, Rotter JI, Liu J, Xu J, Thiery J, Ärnlöv J, Kuusisto J, Jakobsdottir J, Tremblay J, Chambers JC, Whitfield JB, Gaziano JM, Marten J, Coresh J, Jonas JB, Mychaleckyj JC, Christensen K, Eckardt KU, Mohlke KL, Endlich K, Dittrich K, Ryan KA, Rice KM, Taylor KD, Ho K, Nikus K, Matsuda K, Strauch K, Miliku K, Hveem K, Lind L, Wallentin L, Yerges-Armstrong LM, Raffield LM, Phillips LS, Launer LJ, Lyytikäinen LP, Lange LA, Citterio L, Klaric L, Ikram MA, Ising M, Kleber ME, Francescatto M, Concas MP, Ciullo M, Piratsu M, Orho-Melander M, Laakso M, Loeffler M, Perola M, de Borst MH, Gögele M, Bianca M, Lukas MA, Feitosa MF, Biggs ML, Wojczynski MK, Kavousi M, Kanai M, Akiyama M, Yasuda M, Nauck M, Waldenberger M, Chee ML, Chee ML, Boehnke M, Preuss MH, Stumvoll M, Province MA, Evans MK, O'Donoghue ML, Kubo M, Kähönen M, Kastarinen M, Nalls MA, Kuokkanen M, Ghanbari M, Bochud M, Josyula NS, Martin NG, Tan NYQ, Palmer ND, Pirastu N, Schupf N, Verweij N, Hutri-Kähönen N, Mononen N, Bansal N, Devuyst O, Melander O, Raitakari OT, Polasek O, Manunta P, Gasparini P, Mishra PP, Sulem P, Magnusson PKE, Elliott P, Ridker PM, Hamet P, Svensson PO, Joshi PK, Kovacs P, Pramstaller PP, Rossing P, Vollenweider P, van der Harst P, Dorajoo R, Sim RZH, Burkhardt R, Tao R, Noordam R, Mägi R, Schmidt R, de Mutsert R, Rueedi R, van Dam RM, Carroll RJ, Gansevoort RT, Loos RJF, Felicita SC, Sedaghat S, Padmanabhan S, Freitag-Wolf S, Pendergrass SA, Graham SE, Gordon SD, Hwang SJ, Kerr SM, Vaccargiu S, Patil SB, Hallan S, Bakker SJL, Lim SC, Lucae S, Vogelezang S, Bergmann S, Corre T, Ahluwalia TS, Lehtimäki T, Boutin TS, Meitinger T, Wong TY, Bergler T, Rabelink TJ, Esko T, Haller T, Thorsteinsdottir U, Völker U, Foo VHX, Salomaa V, Vitart V, Giedraitis V, Gudnason V, Jaddoe VWV, Huang W, Zhang W, Wei WB, Kiess W, März W, Koenig W, Lieb W, Gao X, Sim X, Wang YX, Friedlander Y, Tham YC, Kamatani Y, Okada Y, Milaneschi Y, Yu Z; Lifelines cohort study; DiscovEHR/MyCode study; VA Million Veteran Program, Stark KJ, Stefansson K, Böger CA, Hung AM, Kronenberg F, Köttgen A, Pattaro C, Heid IM.
Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk
Xiang Shu , Zhishan Chen , Jirong Long , Xingyi Guo , Yaohua Yang , Conghui Qu , Yoon-Ok Ahn , Qiuyin Cai , Graham Casey , Stephen B Gruber , Jeroen R Huyghe , Sun Ha Jee , Mark A Jenkins , Wei-Hua Jia , Keum Ji Jung , Yoichiro Kamatani , Dong-Hyun Kim , Jeongseon Kim , Sun-Seog Kweon , Loic Le Marchand , Koichi Matsuda , Keitaro Matsuo , Polly A Newcomb , Jae Hwan Oh , Jennifer Ose , Isao Oze , Rish K Pai , Zhi-Zhong Pan , Paul D P Pharoah , Mary C Playdon , Ze-Fang Ren , Robert E Schoen , Aesun Shin , Min-Ho Shin , Xiao-Ou Shu , Xiaohui Sun , Catherine M Tangen , Chizu Tanikawa , Cornelia M Ulrich , Franzel J B van Duijnhoven , Bethany Van Guelpen , Alicja Wolk , Michael O Woods , Anna H Wu , Ulrike Peters , Wei Zheng
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Anubha Mahajan , Cassandra N Spracklen , Weihua Zhang , Maggie C Y Ng , Lauren E Petty , Hidetoshi Kitajima , Grace Z Yu , Sina Rüeger , Leo Speidel , Young Jin Kim , Momoko Horikoshi , Josep M Mercader , Daniel Taliun , Sanghoon Moon , Soo-Heon Kwak , Neil R Robertson , Nigel W Rayner , Marie Loh , Bong-Jo Kim , Joshua Chiou , Irene Miguel-Escalada , Pietro Della Briotta Parolo , Kuang Lin , Fiona Bragg , Michael H Preuss , Fumihiko Takeuchi , Jana Nano , Xiuqing Guo , Amel Lamri , Masahiro Nakatochi , Robert A Scott , Jung-Jin Lee , Alicia Huerta-Chagoya , Mariaelisa Graff , Jin-Fang Chai , Esteban J Parra , Jie Yao , Lawrence F Bielak , Yasuharu Tabara , Yang Hai , Valgerdur Steinthorsdottir , James P Cook , Mart Kals , Niels Grarup , Ellen M Schmidt , Ian Pan , Tamar Sofer , Matthias Wuttke , Chloe Sarnowski , Christian Gieger , Darryl Nousome , Stella Trompet , Jirong Long , Meng Sun , Lin Tong , Wei-Min Chen , Meraj Ahmad , Raymond Noordam , Victor J Y Lim , Claudia H T Tam , Yoonjung Yoonie Joo , Chien-Hsiun Chen , Laura M Raffield , Cécile Lecoeur , Bram Peter Prins , Aude Nicolas , Lisa R Yanek , Guanjie Chen , Richard A Jensen , Salman Tajuddin , Edmond K Kabagambe , Ping An , Anny H Xiang , Hyeok Sun Choi , Brian E Cade , Jingyi Tan , Jack Flanagan , Fernando Abaitua , Linda S Adair , Adebowale Adeyemo , Carlos A Aguilar-Salinas , Masato Akiyama , Sonia S Anand , Alain Bertoni , Zheng Bian , Jette Bork-Jensen , Ivan Brandslund , Jennifer A Brody , Chad M Brummett , Thomas A Buchanan , Mickaël Canouil , Juliana C N Chan , Li-Ching Chang , Miao-Li Chee , Ji Chen , Shyh-Huei Chen , Yuan-Tsong Chen , Zhengming Chen , Lee-Ming Chuang , Mary Cushman , Swapan K Das , H Janaka de Silva , George Dedoussis , Latchezar Dimitrov , Ayo P Doumatey , Shufa Du , Qing Duan , Kai-Uwe Eckardt , Leslie S Emery , Daniel S Evans , Michele K Evans , Krista Fischer , James S Floyd , Ian Ford , Myriam Fornage , Oscar H Franco , Timothy M Frayling , Barry I Freedman , Christian Fuchsberger , Pauline Genter , Hertzel C Gerstein , Vilmantas Giedraitis , Clicerio González-Villalpando , Maria Elena González-Villalpando , Mark O Goodarzi , Penny Gordon-Larsen , David Gorkin , Myron Gross , Yu Guo , Sophie Hackinger , Sohee Han , Andrew T Hattersley , Christian Herder , Annie-Green Howard , Willa Hsueh , Mengna Huang , Wei Huang , Yi-Jen Hung , Mi Yeong Hwang , Chii-Min Hwu , Sahoko Ichihara , Mohammad Arfan Ikram , Martin Ingelsson , Md Tariqul Islam , Masato Isono , Hye-Mi Jang , Farzana Jasmine , Guozhi Jiang , Jost B Jonas , Marit E Jørgensen , Torben Jørgensen , Yoichiro Kamatani , Fouad R Kandeel , Anuradhani Kasturiratne , Tomohiro Katsuya , Varinderpal Kaur , Takahisa Kawaguchi , Jacob M Keaton , Abel N Kho , Chiea-Chuen Khor , Muhammad G Kibriya , Duk-Hwan Kim , Katsuhiko Kohara , Jennifer Kriebel , Florian Kronenberg , Johanna Kuusisto , Kristi Läll , Leslie A Lange , Myung-Shik Lee , Nanette R Lee , Aaron Leong , Liming Li , Yun Li , Ruifang Li-Gao , Symen Ligthart , Cecilia M Lindgren , Allan Linneberg , Ching-Ti Liu , Jianjun Liu , Adam E Locke , Tin Louie , Jian'an Luan , Andrea O Luk , Xi Luo , Jun Lv , Valeriya Lyssenko , Vasiliki Mamakou , K Radha Mani , Thomas Meitinger , Andres Metspalu , Andrew D Morris , Girish N Nadkarni , Jerry L Nadler , Michael A Nalls , Uma Nayak , Suraj S Nongmaithem , Ioanna Ntalla , Yukinori Okada , Lorena Orozco , Sanjay R Patel , Mark A Pereira , Annette Peters , Fraser J Pirie , Bianca Porneala , Gauri Prasad , Sebastian Preissl , Laura J Rasmussen-Torvik , Alexander P Reiner , Michael Roden , Rebecca Rohde , Kathryn Roll , Charumathi Sabanayagam , Maike Sander , Kevin Sandow , Naveed Sattar , Sebastian Schönherr , Claudia Schurmann , Mohammad Shahriar , Jinxiu Shi , Dong Mun Shin , Daniel Shriner , Jennifer A Smith , Wing Yee So , Alena Stančáková , Adrienne M Stilp , Konstantin Strauch , Ken Suzuki , Atsushi Takahashi , Kent D Taylor , Barbara Thorand , Gudmar Thorleifsson , Unnur Thorsteinsdottir , Brian Tomlinson , Jason M Torres , Fuu-Jen Tsai , Jaakko Tuomilehto , Teresa Tusie-Luna , Miriam S Udler , Adan Valladares-Salgado , Rob M van Dam , Jan B van Klinken , Rohit Varma , Marijana Vujkovic , Niels Wacher-Rodarte , Eleanor Wheeler , Eric A Whitsel , Ananda R Wickremasinghe , Ko Willems van Dijk , Daniel R Witte , Chittaranjan S Yajnik , Ken Yamamoto , Toshimasa Yamauchi , Loïc Yengo , Kyungheon Yoon , Canqing Yu , Jian-Min Yuan , Salim Yusuf , Liang Zhang , Wei Zheng , FinnGen; eMERGE Consortium; Leslie J Raffel , Michiya Igase , Eli Ipp , Susan Redline , Yoon Shin Cho , Lars Lind , Michael A Province , Craig L Hanis , Patricia A Peyser , Erik Ingelsson , Alan B Zonderman , Bruce M Psaty , Ya-Xing Wang , Charles N Rotimi , Diane M Becker , Fumihiko Matsuda , Yongmei Liu , Eleftheria Zeggini , Mitsuhiro Yokota , Stephen S Rich , Charles Kooperberg , James S Pankow , James C Engert , Yii-Der Ida Chen , Philippe Froguel , James G Wilson , Wayne H H Sheu , Sharon L R Kardia , Jer-Yuarn Wu , M Geoffrey Hayes , Ronald C W Ma , Tien-Yin Wong , Leif Groop , Dennis O Mook-Kanamori , Giriraj R Chandak , Francis S Collins , Dwaipayan Bharadwaj , Guillaume Paré , Michèle M Sale , Habibul Ahsan , Ayesha A Motala , Xiao-Ou Shu , Kyong-Soo Park , J Wouter Jukema , Miguel Cruz , Roberta McKean-Cowdin , Harald Grallert , Ching-Yu Cheng , Erwin P Bottinger , Abbas Dehghan , E-Shyong Tai , Josée Dupuis , Norihiro Kato , Markku Laakso , Anna Köttgen , Woon-Puay Koh , Colin N A Palmer , Simin Liu , Goncalo Abecasis , Jaspal S Kooner , Ruth J F Loos , Kari E North , Christopher A Haiman , Jose C Florez , Danish Saleheen , Torben Hansen , Oluf Pedersen , Reedik Mägi , Claudia Langenberg , Nicholas J Wareham , Shiro Maeda , Takashi Kadowaki , Juyoung Lee , Iona Y Millwood , Robin G Walters , Kari Stefansson , Simon R Myers , Jorge Ferrer , Kyle J Gaulton , James B Meigs , Karen L Mohlke , Anna L Gloyn , Donald W Bowden , Jennifer E Below , John C Chambers , Xueling Sim , Michael Boehnke , Jerome I Rotter , Mark I McCarthy , Andrew P Morris
Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study
Xianyong Yin , Kwangwoo Kim , Hiroyuki Suetsugu , So-Young Bang , Leilei Wen , Masaru Koido , Eunji Ha , Lu Liu , Yuma Sakamoto , Sungsin Jo , Rui-Xue Leng , Nao Otomo , Young-Chang Kwon , Yujun Sheng , Nobuhiko Sugano , Mi Yeong Hwang , Weiran Li , Masaya Mukai , Kyungheon Yoon , Minglong Cai , Kazuyoshi Ishigaki , Won Tae Chung , He Huang , Daisuke Takahashi , Shin-Seok Lee , Mengwei Wang , Kohei Karino , Seung-Cheol Shim , Xiaodong Zheng , Tomoya Miyamura , Young Mo Kang , Dongqing Ye , Junichi Nakamura , Chang-Hee Suh , Yuanjia Tang , Goro Motomura , Yong-Beom Park , Huihua Ding , Takeshi Kuroda , Jung-Yoon Choe , Chengxu Li , Hiroaki Niiro , Youngho Park , Changbing Shen , Takeshi Miyamoto , Ga-Young Ahn , Wenmin Fei , Tsutomu Takeuchi , Jung-Min Shin , Keke Li , Yasushi Kawaguchi , Yeon-Kyung Lee , Yong-Fei Wang , Koichi Amano , Dae Jin Park , Wanling Yang , Yoshifumi Tada , Yu Lung Lau , Ken Yamaji , Zhengwei Zhu , Masato Shimizu , Takashi Atsumi , Akari Suzuki , Takayuki Sumida , Yukinori Okada , Koichi Matsuda , Keitaro Matsuo , Yuta Kochi , Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head; Kazuhiko Yamamoto , Koichiro Ohmura , Tae-Hwan Kim , Sen Yang , Takuaki Yamamoto , Bong-Jo Kim , Nan Shen , Shiro Ikegawa , Hye-Soon Lee , Xuejun Zhang , Chikashi Terao , Yong Cui , Sang-Cheol Bae
A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study
Lu X, Liu Z, Cui Q, Liu F, Li J, Niu X, Shen C, Hu D, Huang K, Chen J, Xing X, Zhao Y, Lu F, Liu X, Cao J, Chen S, Ma H, Yu L, Wu X, Wu X, Li Y, Zhang H, Mo X, Zhao L, Huang J, Wang L, Wen W, Shu XO, Takeuchi F, Koh WP, Tai ES, Cheng CY, Wong TY, Chang X, Chan MY, Gao W, Zheng H, Chen K, Chen J, He J, Tang CS, Lam KSL, Tse HF, Cheung CYY, Takahashi A, Kubo M, Kato N, Terao C, Kamatani Y, Sham PC, Heng CK, Hu Z, Chen YE, Wu T, Shen H, Willer CJ, Gu D.
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores
Weissbrod O, Kanai M, Shi H, Gazal S, Peyrot WJ, Khera AV, Okada Y; Biobank Japan Project, Martin AR, Finucane HK, Price AL.
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kučinskas V, Kučinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M Jr, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadić I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbaşoğlu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, Müller-Myhsok B, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S; Indonesia Schizophrenia Consortium; PsychENCODE; Psychosis Endophenotypes International Consortium; SynGO Consortium, Adolfsson R, Arango C, Baune BT, Belangero SI, Børglum AD, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Ehrenreich H, Escott-Price V, Esko T, Fanous AH, Gareeva A, Gawlik M, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, Jönsson EG, Kahn RS, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Krebs MO, Laurent-Levinson C, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Menezes PR, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, Nöthen MM, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stefánsson H, Stefansson K, Tsuang MT, van Os J, Vawter MP, Weinberger DR, Werge T, Wildenauer DB, Yu X, Yue W, Holmans PA, Pocklington AJ, Roussos P, Vassos E, Verhage M, Visscher PM, Yang J, Posthuma D, Andreassen OA, Kendler KS, Owen MJ, Wray NR, Daly MJ, Huang H, Neale BM, Sullivan PF, Ripke S, Walters JTR, O'Donovan MC; Schizophrenia Working Group of the Psychiatric Genomics Consortium.
Editorial: Current Status and Future Challenges of Biobank Data Analysis
Lu TP, Kamatani Y, Belbin G, Park T, Hsiao CK.
Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants
Yukihide Momozawa, Rumi Sasai, Yoshiaki Usui, Kouya Shiraishi, Yusuke Iwasaki, Yukari Taniyama, Michael T. Parsons, Keijiro Mizukami, Yuya Sekine, Makoto Hirata, Yoichiro Kamatani, Mikiko Endo, Chihiro Inai, Sadaaki Takata, Hidemi Ito, Takashi Kohno, Koichi Matsuda, Seigo Nakamura, Kokichi Sugano, Teruhiko Yoshida, Hidewaki Nakagawa, Keitaro Matsuo, Yoshinori Murakami, Amanda B. Spurdle, Michiaki Kubo
Genome-wide risk prediction of common diseases across ancestries in one million people.
Mars N, Kerminen S, Feng YA, Kanai M, Läll K, Thomas LF, Skogholt AH, Della Briotta Parolo P; Biobank Japan Project; FinnGen, Neale BM, Smoller JW, Gabrielsen ME, Hveem K, Mägi R, Matsuda K, Okada Y, Pirinen M, Palotie A, Ganna A, Martin AR, Ripatti S.
Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682
Dawed AY, Yee SW, Zhou K, van Leeuwen N, Zhang Y, Siddiqui MK, Etheridge A, Innocenti F, Xu F, Li JH, Beulens JW, van der Heijden AA, Slieker RC, Chang YC, Mercader JM, Kaur V, Witte JS, Lee MTM, Kamatani Y, Momozawa Y, Kubo M, Palmer CNA, Florez JC, Hedderson MM, 't Hart LM, Giacomini KM, Pearson ER; for MetGen Plus, for the DIRECT Consortium.
Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer
Keiko Hikino, Masaru Koido, Nao Otomo, Kohei Tomizuka, Shiro Ikegawa, Koichi Matsuda, Yukihide Momozawa, Biobank Japan Project; Taisei Mushiroda, Chikashi Terao
Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort
JamesCasaletto, MichaelParsons, CharlesMarkello, YusukeIwasaki, YukihideMomozawa, Amanda B.Spurdle, MelissaCline
Whole exome analysis of patients in Japan with hearing loss reveals high heterogeneity among responsible and novel candidate genes
Hideki Mutai, Yukihide Momozawa, Yoichiro Kamatani, Atsuko Nakano, Hirokazu Sakamoto, Tetsuya Takiguchi, Kiyomitsu Nara, Michiaki Kubo & Tatsuo Matsunaga
[Cohorts and Biobanks as Essential Resources for Cancer Research]
Yoshinori Murakami
A single-nucleotide-polymorphism in the 5'-flanking region of MSX1 gene as a predictive marker candidate for platinum-based therapy of esophageal carcinoma
Takahiro Mori, Kazuko Ueno, Katsushi Tokunaga, Yosuke Kawai, Koichi Matsuda, Nao Nishida, Keigo Komine, Sakae Saito, Masao Nagasaki, BioBank Japan Project
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease
Jie Zheng , Yuemiao Zhang , Humaira Rasheed , Venexia Walker , Yuka Sugawara , Jiachen Li , Yue Leng , Benjamin Elsworth , Robyn E Wootton , Si Fang , Qian Yang , Stephen Burgess , Philip C Haycock , Maria Carolina Borges , Yoonsu Cho , Rebecca Carnegie , Amy Howell , Jamie Robinson , Laurent F Thomas , Ben Michael Brumpton , Kristian Hveem , Stein Hallan , Nora Franceschini , Andrew P Morris , Anna Köttgen , Cristian Pattaro , Matthias Wuttke , Masayuki Yamamoto , Naoki Kashihara , Masato Akiyama , Masahiro Kanai , Koichi Matsuda , Yoichiro Kamatani , Yukinori Okada , Robin Walters , Iona Y Millwood , Zhengming Chen , George Davey Smith , Sean Barbour , Canqing Yu , Bjørn Olav Åsvold , Hong Zhang , Tom R Gaunt
