Genome-wide Association Studies Categorized by Class of Antihypertensive Drugs Reveal Complex Pathogenesis of Hypertension with Drug Resistance

Keiko Yamazaki, Chikashi Terao, Atsushi Takahashi, et al.

• PMID: 37151119

Hyperfructosemia in Sleep Disordered Breathing: Metabolome Analysis of Nagahama Study

Yoshinari Nakatsuka, Kimihiko Murase, Kazuhiro Sonomura, et al.

• PMID: 37543666

A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants

Jaeyong Choi, Sungjae Kim, Juhyun Kim, et al.

• PMID: 37556544

Contribution of an Asian-prevalent HLA haplotype to the risk of HBV-related hepatocellular carcinoma

Atsushi Kawamura, Koichi Matsuda, Yoshinori Murakami, et al.

• PMID: 37558689

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

Lenka Stolarova, Petra Kleiblova, Petra Zemankova, et al.

• PMID: 37449874

Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects

Shuji Ito, Xiaoxi Liu, Yuki Ishikawa, et al.

• PMID: 37612283

GWAS Meta-Analysis of Over 29,000 People with Epilepsy Identifies 26 Risk Loci and Subtype-Specific Genetic Architecture

International League Against Epilepsy Consortium on Complex Epilepsies.

• PMID: 37653029

Multi-Ancestry Genome-Wide Analysis Identifies Shared Genetic Effects and Common Genetic Variants for Self-Reported Sleep Duration

B. H. Scammell, C. Tchio, Y. Song, et al.

• PMID: 37384397

Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores

Adrian I. Campos, Shinichi Namba, Shu-Chin Lin, et al.

• PMID: 37723263

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Minta Thomas, Yu-Ru Su, Elisabeth A. Rosenthal, et al.

• PMID: 37783704

Natural Selection Signatures in the Hondo and Ryukyu Japanese Subpopulations

Xiaoxi Liu, Masatoshi Matsunami, Momoko Horikoshi, et al.

• PMID: 37903429

Polygenic Prediction Across Populations is Influenced by Ancestry, Genetic Architecture, and Methodology

Ying Wang, Masahiro Kanai, Taotao Tan, et al.

• PMID: 37868036

Identification of Telomere Maintenance Gene Variations Related to Lung Adenocarcinoma Risk by Genome-Wide Association and Whole Genome Sequencing Analyses

Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, et al.

• PMID: 37882647

A large-scale microRNA transcriptome-wide association study identifies two susceptibility microRNAs, miR-1307-5p and miR-192-3p, for colorectal cancer risk

Zhishan Chen, Weiqiang Lin, Qiuyin Cai, et al.

• PMID: 37903058

Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping

Hiroaki Tanaka, Yukinori Okada, Shingo Nakayamada, et al.

• PMID: 37903543

Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

Anqi Wang, Jiayi Shen, Alex A. Rodriguez, et al.

• PMID: 37945903

East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease

Yunye He, Masaru Koido, Yoichi Sutoh, et al.

• PMID: 38036781

Genetic Risk Score of Cerebral Infarction in Atrial Fibrillation Genome-Wide Association Study

Yusuke Ebana, Lian Liu, Kensuke Ihara, et al.

• PMID: 37638535

Genetic insights into ossification of the posterior longitudinal ligament of the spine

Yoshinao Koike, Masahiko Takahata, Masahiro Nakajima, et al.

• PMID: 37461309

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

Krishna G. Aragam, Tao Jiang, Anuj Goel, et al.

• PMID: 36474045

Genetic diversity fuels gene discovery for tobacco and alcohol use

Gretchen R. B. Saunders, Xingyan Wang, Fang Chen, et al.

• PMID: 36477530

Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus

Hiroyuki Suetsugu, Kwangwoo Kim, Takuaki Yamamoto, et al.

• PMID: 34850884

Genetic Architectures Underlie Onset Age of Atopic Dermatitis

Keiko Hikino, Nao Tanaka, Masaru Koido, et al.

• PMID: 35841947

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Kazuyoshi Ishigaki, Saori Sakaue, Chikashi Terao, et al.

• PMID: 36333501

Association between germline pathogenic variants in cancer-predisposing genes and lymphoma risk

Yoshiaki Usui, Yusuke Iwasaki, Keitaro Matsuo, et al.

• PMID: 36065483

Population-based Screening for Hereditary Colorectal Cancer Variants in Japan

Masashi Fujita, Xiaoxi Liu, Yusuke Iwasaki, et al.

• PMID: 33309985

Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, et al.

• PMID: 36180795

DOCK2 is involved in the host genetics and biology of severe COVID-19

Ho Namkoong, Ryuya Edahiro, Tomomi Takano, et al.

• PMID: 35940203

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

Catherine Tcheandjieu, Xiang Zhu, Austin T. Hilliard, et al.

• PMID: 35915156

Genetic analysis of right heart structure and function in 40,000 people

James P. Pirruccello, Paolo Di Achille, Victor Nauffal, et al.

• PMID: 35697867

Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians

Jie Ping, Yaohua Yang, Wanqing Wen, et al.

• PMID: 35765848

Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component

Yuya Shirai, Yoshimitsu Nakanishi, Akari Suzuki, et al.

• PMID: 35753705

Association of germline TYK2 variation with lung cancer and non-Hodgkin lymphoma risk

James Yarmolinsky, Christopher I. Amos, Rayjean J. Hung, et al.

• PMID: 35747941

Different risk genes contribute to clear cell and non-clear cell renal cell carcinoma in 1532 Japanese patients and 5996 controls

Yuya Sekine, Yusuke Iwasaki, Tomomi Aoi, et al.

• PMID: 35764097

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Thomas W. Winkler, Humaira Rasheed, Alexander Teumer, et al.

• PMID: 35697829

Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk

Xiang Shu, Zhishan Chen, Jirong Long, et al.

• PMID: 35266989

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Anubha Mahajan, Cassandra N. Spracklen, Weihua Zhang, et al.

• PMID: 35551307

Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study

Xianyong Yin, Kwangwoo Kim, Hiroyuki Suetsugu, et al.

• PMID: 35609976

A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study

Xiangfeng Lu, Zhongying Liu, Qingmei Cui, et al.

• PMID: 35195259

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

Omer Weissbrod, Masahiro Kanai, Huwenbo Shi, et al.

• PMID: 35393596

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Vassily Trubetskoy, Antonio F. Pardiñas, Ting Qi, et al.

• PMID: 35396580

Editorial: Current Status and Future Challenges of Biobank Data Analysis

Tzu-Pin Lu, Yoichiro Kamatani, Gillian Belbin, et al.

• PMID: 35495141

Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants

Yukihide Momozawa, Rumi Sasai, Yoshiaki Usui, et al.

• PMID: 35420638

Genome-wide risk prediction of common diseases across ancestries in one million people

Nina Mars, Sini Kerminen, Yen-Chen A. Feng, et al.

• PMID: 35591975

Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682

Adem Y. Dawed, Sook Wah Yee, Kaixin Zhou, et al.

• PMID: 35349657

Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer

Keiko Hikino, Masaru Koido, Nao Otomo, et al.

• PMID: 34671089

Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort

James Casaletto, Michael Parsons, Charles Markello, et al.

• PMID: 35373174

Whole exome analysis of patients in Japan with hearing loss reveals high heterogeneity among responsible and novel candidate genes

Hideki Mutai, Yukihide Momozawa, Yoichiro Kamatani, et al.

• PMID: 35248088

[Cohorts and Biobanks as Essential Resources for Cancer Research]

Yoshinori Murakami.

• PMID: 35249044

A single-nucleotide-polymorphism in the 5′-flanking region of MSX1 gene as a predictive marker candidate for platinum-based therapy of esophageal carcinoma

Takahiro Mori, Kazuko Ueno, Katsushi Tokunaga, et al.

• PMID: 35251318