Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

Ying Wang, Masahiro Kanai, Taotao Tan, et al.

• PMID: 37868036

Natural Selection Signatures in the Hondo and Ryukyu Japanese Subpopulations

Xiaoxi Liu, Masatoshi Matsunami, Momoko Horikoshi, et al.

• PMID: 37903429

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Minta Thomas, Yu-Ru Su, Elisabeth A. Rosenthal, et al.

• PMID: 37783704

Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores

Adrian I. Campos, Shinichi Namba, Shu-Chin Lin, et al.

• PMID: 37723263

Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration

B. H. Scammell, C. Tchio, Y. Song, et al.

• PMID: 37384397

GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture

International League Against Epilepsy Consortium on Complex Epilepsies.

• PMID: 37653029

Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects

Shuji Ito, Xiaoxi Liu, Yuki Ishikawa, et al.

• PMID: 37612283

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

Lenka Stolarova, Petra Kleiblova, Petra Zemankova, et al.

• PMID: 37449874

A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants

Jaeyong Choi, Sungjae Kim, Juhyun Kim, et al.

• PMID: 37556544

Contribution of an Asian-prevalent HLA haplotype to the risk of HBV-related hepatocellular carcinoma

Atsushi Kawamura, Koichi Matsuda, Yoshinori Murakami, et al.

• PMID: 37558689

Genome-wide Association Studies Categorized by Class of Antihypertensive Drugs Reveal Complex Pathogenesis of Hypertension with Drug Resistance

Keiko Yamazaki, Chikashi Terao, Atsushi Takahashi, et al.

• PMID: 37151119

Hyperfructosemia in sleep disordered breathing: metabolome analysis of Nagahama study

Yoshinari Nakatsuka, Kimihiko Murase, Kazuhiro Sonomura, et al.

• PMID: 37543666

GWAS of Folate Metabolism with Gene-Environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese – the J-MICC Study

Mineko Tsukamoto, Asahi Hishida, Takashi Tamura, et al.

• PMID: 37517992

Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis

Yoshiyuki Akiyama, Kyuto Sonehara, Daichi Maeda, et al.

• PMID: 37467720

Genetic insights into ossification of the posterior longitudinal ligament of the spine

Yoshinao Koike, Masahiko Takahata, Masahiro Nakajima, et al.

• PMID: 37461309

Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis

Go Sato, Yuya Shirai, Shinichi Namba, et al.

• PMID: 37340002

Evidence of causality of low body mass index on risk of adolescent idiopathic scoliosis: a Mendelian randomization study

Nao Otomo, Anas M. Khanshour, Masaru Koido, et al.

• PMID: 37415668

Detection of trait-associated structural variations using short-read sequencing

Shunichi Kosugi, Yoichiro Kamatani, Katsutoshi Harada, et al.

• PMID: 37388916

Improved genetic prediction of the risk of knee osteoarthritis using the risk factor-based polygenic score

Yugo Morita, Yoichiro Kamatani, Hiromu Ito, et al.

• PMID: 37309008

Prediction of the cell-type-specific transcription of non-coding RNAs from genome sequences via machine learning

Masaru Koido, Chung-Chau Hon, Satoshi Koyama, et al.

• PMID: 36411359

Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk

Shohei Kojima, Satoshi Koyama, Mirei Ka, et al.

• PMID: 37169872

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study

Shogo Dofuku, Kyuto Sonehara, Satoru Miyawaki, et al.

• PMID: 35701560

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, et al.

• PMID: 37236969

Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation

Akiko Hanyuda, Atsushi Goto, Ryoko Katagiri, et al.

• PMID: 37120602

Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants

Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, et al.

• PMID: 34421081

Genetic Risk of Primary Aldosteronism and its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies

Tatsuhiko Naito, Kosuke Inoue, Kyuto Sonehara, et al.

• PMID: 36802911

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

Takuya Sakashita, Yasuyuki Nakamura, Yoichi Sutoh, et al.

• PMID: 37090135

Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer

Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, et al.

• PMID: 36988593

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Mark K. Bakker, Jos P. Kanning, Gad Abraham, et al.

• PMID: 36655558

Prediction Model with HLA-A*33:03 Reveals Number of Days to Develop Liver Cancer from Blood Test

Nao Nishida, Jun Ohashi, Goki Suda, et al.

• PMID: 36902191

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Nilufer Rahmioglu, Sally Mortlock, Marzieh Ghiasi, et al.

• PMID: 36914876

Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals

Masato Akiyama, Saori Sakaue, Atsushi Takahashi, et al.

• PMID: 36737517

Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention

Nicholas A. Marston, James P. Pirruccello, Giorgio E. M. Melloni, et al.

• PMID: 36576811

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction

Kazuo Miyazawa, Kaoru Ito, Masamichi Ito, et al.

• PMID: 36653681

Hereditary cancer variants and homologous recombination deficiency in biliary tract cancer

Yuki Okawa, Yusuke Iwasaki, Todd A Johnson, et al.

• PMID: 36243179

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Ying Wang, Shinichi Namba, Esteban Lopera, et al.

• PMID: 36777179

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes

Yoshihiko Tomofuji, Ken Suzuki, Toshihiro Kishikawa, et al.

• PMID: 36624208

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population

Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, et al.

• PMID: 36162535

Genetic footprints of assortative mating in the Japanese population

Kenichi Yamamoto, Kyuto Sonehara, Shinichi Namba, et al.

• PMID: 36138222

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

Krishna G. Aragam, Tao Jiang, Anuj Goel, et al.

• PMID: 36474045

Genetic diversity fuels gene discovery for tobacco and alcohol use

Gretchen R. B. Saunders, Xingyan Wang, Fang Chen, et al.

• PMID: 36477530

Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus

Hiroyuki Suetsugu, Kwangwoo Kim, Takuaki Yamamoto, et al.

• PMID: 34850884

Genetic Architectures Underlie Onset Age of Atopic Dermatitis

Keiko Hikino, Nao Tanaka, Masaru Koido, et al.

• PMID: 35841947

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Kazuyoshi Ishigaki, Saori Sakaue, Chikashi Terao, et al.

• PMID: 36333501

Association between germline pathogenic variants in cancer-predisposing genes and lymphoma risk

Yoshiaki Usui, Yusuke Iwasaki, Keitaro Matsuo, et al.

• PMID: 36065483

Population-based Screening for Hereditary Colorectal Cancer Variants in Japan

Masashi Fujita, Xiaoxi Liu, Yusuke Iwasaki, et al.

• PMID: 33309985

Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, et al.

• PMID: 36180795

DOCK2 is involved in the host genetics and biology of severe COVID-19

Ho Namkoong, Ryuya Edahiro, Tomomi Takano, et al.

• PMID: 35940203

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

Catherine Tcheandjieu, Xiang Zhu, Austin T. Hilliard, et al.

• PMID: 35915156

Genetic analysis of right heart structure and function in 40,000 people

James P. Pirruccello, Paolo Di Achille, Victor Nauffal, et al.

• PMID: 35697867