Identification of an novel genetic variant associated with osteoporosis: insights from the Taiwan Biobank Study

Yi-Ching Liaw, Koichi Matsuda and Yung-Po Liaw.

• PMID: 38655459

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Zhishan Chen, Xingyi Guo, Ran Tao, et al.

• PMID: 38670944

Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

Mark P. Purdue, Diptavo Dutta, Mitchell J. Machiela, et al.

• PMID: 38671320

Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencing

Xiaoxi Liu, Satoshi Koyama, Kohei Tomizuka, et al.

• PMID: 38630824

Poor accuracy and sustainability of the first-step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population

Antonio De Vincentis, Federica Tavaglione, Shinichi Namba, et al.

• PMID: 38497224

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, et al.

• PMID: 38374256

Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation

Valeria Lo Faro, Arjun Bhattacharya, Wei Zhou, et al.

• PMID: 38382466

GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, et al.

• PMID: 38296975

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Rosalie B. T. M. Sterenborg, Inga Steinbrenner, Yong Li, et al.

• PMID: 38291025

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people

Yuriko N. Koyanagi, Masahiro Nakatochi, Shinichi Namba, et al.

• PMID: 38277453

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

Markus Scholz, Katrin Horn, Janne Pott, et al.

• PMID: 38233393

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, et al.

• PMID: 38177345

Genetic risk score of cerebral infarction in atrial fibrillation genome-wide association study

Yusuke Ebana, Lian Liu, Kensuke Ihara, et al.

• PMID: 37638535

East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease

Yunye He, Masaru Koido, Yoichi Sutoh, et al.

• PMID: 38036781

Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

Anqi Wang, Jiayi Shen, Alex A. Rodriguez, et al.

• PMID: 37945903

A large-scale microRNA transcriptome-wide association study identifies two susceptibility microRNAs, miR-1307-5p and miR-192-3p, for colorectal cancer risk

Zhishan Chen, Weiqiang Lin, Qiuyin Cai, et al.

• PMID: 37903058

Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping

Hiroaki Tanaka, Yukinori Okada, Shingo Nakayamada, et al.

• PMID: 37903543

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, et al.

• PMID: 37882647

Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

Ying Wang, Masahiro Kanai, Taotao Tan, et al.

• PMID: 37868036

Natural Selection Signatures in the Hondo and Ryukyu Japanese Subpopulations

Xiaoxi Liu, Masatoshi Matsunami, Momoko Horikoshi, et al.

• PMID: 37903429

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Minta Thomas, Yu-Ru Su, Elisabeth A. Rosenthal, et al.

• PMID: 37783704

Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores

Adrian I. Campos, Shinichi Namba, Shu-Chin Lin, et al.

• PMID: 37723263

Multi-ancestry genome-wide analysis identifies shared genetic effects and common genetic variants for self-reported sleep duration

B. H. Scammell, C. Tchio, Y. Song, et al.

• PMID: 37384397

GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture

International League Against Epilepsy Consortium on Complex Epilepsies.

• PMID: 37653029

Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects

Shuji Ito, Xiaoxi Liu, Yuki Ishikawa, et al.

• PMID: 37612283

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

Lenka Stolarova, Petra Kleiblova, Petra Zemankova, et al.

• PMID: 37449874

A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants

Jaeyong Choi, Sungjae Kim, Juhyun Kim, et al.

• PMID: 37556544

Contribution of an Asian-prevalent HLA haplotype to the risk of HBV-related hepatocellular carcinoma

Atsushi Kawamura, Koichi Matsuda, Yoshinori Murakami, et al.

• PMID: 37558689

Genome-wide Association Studies Categorized by Class of Antihypertensive Drugs Reveal Complex Pathogenesis of Hypertension with Drug Resistance

Keiko Yamazaki, Chikashi Terao, Atsushi Takahashi, et al.

• PMID: 37151119

Hyperfructosemia in sleep disordered breathing: metabolome analysis of Nagahama study

Yoshinari Nakatsuka, Kimihiko Murase, Kazuhiro Sonomura, et al.

• PMID: 37543666

GWAS of Folate Metabolism with Gene-Environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese – the J-MICC Study

Mineko Tsukamoto, Asahi Hishida, Takashi Tamura, et al.

• PMID: 37517992

Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis

Yoshiyuki Akiyama, Kyuto Sonehara, Daichi Maeda, et al.

• PMID: 37467720

Genetic insights into ossification of the posterior longitudinal ligament of the spine

Yoshinao Koike, Masahiko Takahata, Masahiro Nakajima, et al.

• PMID: 37461309

Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis

Go Sato, Yuya Shirai, Shinichi Namba, et al.

• PMID: 37340002

Evidence of causality of low body mass index on risk of adolescent idiopathic scoliosis: a Mendelian randomization study

Nao Otomo, Anas M. Khanshour, Masaru Koido, et al.

• PMID: 37415668

Detection of trait-associated structural variations using short-read sequencing

Shunichi Kosugi, Yoichiro Kamatani, Katsutoshi Harada, et al.

• PMID: 37388916

Improved genetic prediction of the risk of knee osteoarthritis using the risk factor-based polygenic score

Yugo Morita, Yoichiro Kamatani, Hiromu Ito, et al.

• PMID: 37309008

Prediction of the cell-type-specific transcription of non-coding RNAs from genome sequences via machine learning

Masaru Koido, Chung-Chau Hon, Satoshi Koyama, et al.

• PMID: 36411359

Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk

Shohei Kojima, Satoshi Koyama, Mirei Ka, et al.

• PMID: 37169872

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study

Shogo Dofuku, Kyuto Sonehara, Satoru Miyawaki, et al.

• PMID: 35701560

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, et al.

• PMID: 37236969

Investigating the association between glycaemic traits and colorectal cancer in the Japanese population using Mendelian randomisation

Akiko Hanyuda, Atsushi Goto, Ryoko Katagiri, et al.

• PMID: 37120602

Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants

Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, et al.

• PMID: 34421081

Genetic Risk of Primary Aldosteronism and its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies

Tatsuhiko Naito, Kosuke Inoue, Kyuto Sonehara, et al.

• PMID: 36802911

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

Takuya Sakashita, Yasuyuki Nakamura, Yoichi Sutoh, et al.

• PMID: 37090135

Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer

Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, et al.

• PMID: 36988593

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Mark K. Bakker, Jos P. Kanning, Gad Abraham, et al.

• PMID: 36655558

Prediction Model with HLA-A*33:03 Reveals Number of Days to Develop Liver Cancer from Blood Test

Nao Nishida, Jun Ohashi, Goki Suda, et al.

• PMID: 36902191

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Nilufer Rahmioglu, Sally Mortlock, Marzieh Ghiasi, et al.

• PMID: 36914876

Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals

Masato Akiyama, Saori Sakaue, Atsushi Takahashi, et al.

• PMID: 36737517