Genetic legacy of ancient hunter-gatherer Jomon in Japanese populations

Kenichi Yamamoto, Shinichi Namba, Kyuto Sonehara, et al.

• PMID: 39532881

Inconsistent embryo selection across polygenic score methods

Shinichi Namba, Masato Akiyama, Haruka Hamanoue, et al.

• PMID: 39402258

Population-specific putative causal variants shape quantitative traits

Satoshi Koyama, Xiaoxi Liu, Yoshinao Koike, et al.

• PMID: 39363016

Genome-wide association studies for pelvic organ prolapse in the Japanese population

Masatoshi Matsunami, Minako Imamura, Asuka Ashikari, et al.

• PMID: 39349682

Machine learning reveals heterogeneous associations between environmental factors and cardiometabolic diseases across polygenic risk scores

Tatsuhiko Naito, Kosuke Inoue, Shinichi Namba, et al.

• PMID: 39304733

Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome‐Wide Association and Mendelian Randomization Study

Kosuke Inoue, Tatsuhiko Naito, Ryosuke Fuji, et al.

• PMID: 39101507

Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease

Rainer Malik, Nathalie Beaufort, Jiang Li, et al.

• PMID: 39196222

Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues

Yoshihiko Tomofuji, Ryuya Edahiro, Kyuto Sonehara, et al.

• PMID: 39084228

Genetic Risk Stratification of Primary Open-Angle Glaucoma in Japanese Individuals

Masato Akiyama, Gen Tamiya, Kohta Fujiwara, et al.

• PMID: 39023470

Common and rare genetic variants predisposing females to unexplained recurrent pregnancy loss

Kyuto Sonehara, Yoshitaka Yano, Tatsuhiko Naito, et al.

• PMID: 39019884

Genome-wide association study on meningioma risk in Japan: a multicenter prospective study

Shuhei Yamada, Toru Umehara, Kyuto Sonehara, et al.

PMID: 39002029

Polygenic risk score for blood pressure and lifestyle factors with overall and CVD mortality: a prospective cohort study in a Japanese population

Ryosuke Fujii, Asahi Hishida, Masahiro Nakatochi, et al.

• PMID: 38961281

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

Katherine A. Kentistou, Lena R. Kaisinger, Stasa Stankovic, et al.

• PMID: 38951643

Genome-Wide Association Study with Three Control Cohorts of Japanese Patients with Esotropia and Exotropia of Comitant Strabismus and Idiopathic Superior Oblique Muscle Palsy

Toshihiko Matsuo, Ichiro Hamasaki, Yoichiro Kamatani, et al.

• PMID: 39000095

Genetic Risk, Healthy Lifestyle Adherence, and Risk of Developing Diabetes in the Japanese Population

Masato Takase, Naoki Nakaya, Tomohiro Nakamura, et al.

• PMID: 38910120

RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial Infarction

Keiko Hikino, Satoshi Koyama, Kaoru Ito, et al.

• PMID: 38888930

Body mass index stratification optimizes polygenic prediction of type 2 diabetes in cross-biobank analyses

Takafumi Ojima, Shinichi Namba, Ken Suzuki, et al.

• PMID: 38862855

Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

Mark P. Purdue, Diptavo Dutta, Mitchell J. Machiela, et al.

• PMID: 38671320

Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencing

Xiaoxi Liu, Satoshi Koyama, Kohei Tomizuka, et al.

• PMID: 38630824

Poor accuracy and sustainability of the first-step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population

Antonio De Vincentis, Federica Tavaglione, Shinichi Namba, et al.

• PMID: 38497224

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, et al.

• PMID: 38374256

GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, et al.

• PMID: 38296975

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people

Yuriko N. Koyanagi, Masahiro Nakatochi, Shinichi Namba, et al.

• PMID: 38277453

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, et al.

• PMID: 38177345

Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention

Nicholas A. Marston, James P. Pirruccello, Giorgio E. M. Melloni, et al.

• PMID: 36576811

Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals

Masato Akiyama, Saori Sakaue, Atsushi Takahashi, et al.

• PMID: 36737517

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction

Kazuo Miyazawa, Kaoru Ito, Masamichi Ito, et al.

• PMID: 36653681

Hereditary Cancer Variants and Homologous Recombination Deficiency in Biliary Tract Cancer

Yuki Okawa, Yusuke Iwasaki, Todd A Johnson, et al.

• PMID: 36243179

Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer

Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, et al.

• PMID: 36988593

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Mark K. Bakker, Jos P. Kanning, Gad Abraham, et al.

• PMID: 36655558

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Nilufer Rahmioglu, Sally Mortlock, Marzieh Ghiasi, et al.

• PMID: 36914876

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population

Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, et al.

• PMID: 36162535

Genetic footprints of assortative mating in the Japanese population

Kenichi Yamamoto, Kyuto Sonehara, Shinichi Namba, et al.

• PMID: 36138222

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Ying Wang, Shinichi Namba, Esteban Lopera, et al.

• PMID: 36777179

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes

Yoshihiko Tomofuji, Ken Suzuki, Toshihiro Kishikawa, et al.

• PMID: 36624208

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

Takuya Sakashita, Yasuyuki Nakamura, Yoichi Sutoh, et al.

• PMID: 37090135

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study

Shogo Dofuku, Kyuto Sonehara, Satoru Miyawaki, et al.

• PMID: 35701560

Evidence of causality of low body mass index on risk of adolescent idiopathic scoliosis: a Mendelian randomization study

Nao Otomo, Anas M. Khanshour, Masaru Koido, et al.

• PMID: 37415668

Prediction Model with HLA-A*33:03 Reveals Number of Days to Develop Liver Cancer from Blood Test

Nao Nishida, Jun Ohashi, Goki Suda, et al.

• PMID: 36902191

Genetic Risk of Primary Aldosteronism and its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies

Tatsuhiko Naito, Kosuke Inoue, Kyuto Sonehara, et al.

• PMID: 36802911

Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants

Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, et al.

• PMID: 34421081

Investigating the Association between Glycaemic Traits and Colorectal Cancer in the Japanese Population using Mendelian Randomisation

Akiko Hanyuda, Atsushi Goto, Ryoko Katagiri, et al.

• PMID: 37120602

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, et al.

• PMID: 37236969

Mobile Element Variation Contributes to Population-Specific Genome Diversification, Gene Regulation and Disease Risk

Shohei Kojima, Satoshi Koyama, Mirei Ka, et al.

• PMID: 37169872

Prediction of the Cell-Type-Specific Transcription of Non-Coding RNAs from Genome Sequences Via Machine Learning

Masaru Koido, Chung-Chau Hon, Satoshi Koyama, et al.

• PMID: 36411359

Improved Genetic Prediction of the Risk of Knee Osteoarthritis using the Risk Factor-Based Polygenic Score

Yugo Morita, Yoichiro Kamatani, Hiromu Ito, et al.

• PMID: 37309008

Detection of trait-associated structural variations using short-read sequencing

Shunichi Kosugi, Yoichiro Kamatani, Katsutoshi Harada, et al.

• PMID: 37388916

Pan-Cancer and Cross-Population Genome-Wide Association Studies Dissect Shared Genetic Backgrounds Underlying Carcinogenesis

Go Sato, Yuya Shirai, Shinichi Namba, et al.

• PMID: 37340002

Genome-Wide Association Study Identifies Risk Loci within the Major Histocompatibility Complex Region for Hunner-Type Interstitial Cystitis

Yoshiyuki Akiyama, Kyuto Sonehara, Daichi Maeda, et al.

• PMID: 37467720

GWAS of Folate Metabolism with Gene-Environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese – the J-MICC Study

Mineko Tsukamoto, Asahi Hishida, Takashi Tamura, et al.

• PMID: 37517992