Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

Mark P. Purdue, Diptavo Dutta, Mitchell J. Machiela, et al.

• PMID: 38671320

Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencing

Xiaoxi Liu, Satoshi Koyama, Kohei Tomizuka, et al.

• PMID: 38630824
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Poor accuracy and sustainability of the first-step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population

Antonio De Vincentis, Federica Tavaglione, Shinichi Namba, et al.

• PMID: 38497224

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, et al.

• PMID: 38374256

GWAS for Systemic Sclerosis Identifies Six Novel Susceptibility Loci Including One in the Fcγ Receptor Region

Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, et al.

• PMID: 38296975　
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Genetic Architecture of Alcohol Consumption Identified by a Genotype-Stratified GWAS and Impact on Esophageal Cancer Risk in Japanese People

Yuriko N. Koyanagi, Masahiro Nakatochi, Shinichi Namba, et al.

• PMID: 38277453

Multi-Ancestry Genome-Wide Association Study of Major Depression Aids Locus Discovery, Fine Mapping, Gene Prioritization and Causal Inference

Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, et al.

• PMID: 38177345

Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention

Nicholas A Marston, James P Pirruccello, Giorgio E M Melloni, et al.

• PMID: 36576811

Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals

Masato Akiyama, Saori Sakaue, Atsushi Takahashi, et al.

• PMID: 36737517

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction

Kazuo Miyazawa, Kaoru Ito, Masamichi Ito, et al.

• PMID: 36653681
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Hereditary Cancer Variants and Homologous Recombination Deficiency in Biliary Tract Cancer

Yuki Okawa, Yusuke Iwasaki, Todd A Johnson, et al.

• PMID: 36243179
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Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer

Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, et al.

• PMID: 36988593
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Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Mark K. Bakker, Jos P. Kanning, Gad Abraham, et al.

• PMID: 36655558

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Nilufer Rahmioglu, Sally Mortlock, Marzieh Ghiasi, et al.

• PMID: 36914876

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population

Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, et al.

• PMID: 36162535

Genetic footprints of assortative mating in the Japanese population

Kenichi Yamamoto, Kyuto Sonehara, Shinichi Namba, et al.

• PMID: 36138222
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Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Ying Wang , Shinichi Namba , Esteban Lopera, et al.

• PMID: 36777179

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes

Yoshihiko Tomofuji, Ken Suzuki, Toshihiro Kishikawa, et al.

• PMID: 36624208

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

Takuya Sakashita, Yasuyuki Nakamura, Yoichi Sutoh, et al.

• PMID: 37090135

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study

Shogo Dofuku, Kyuto Sonehara, Satoru Miyawaki, et al.

• PMID: 35701560

Evidence of Causality of Low Body Mass Index on Risk of Adolescent Idiopathic Scoliosis: A Mendelian Randomization Study

Nao Otomo, Anas M. Khanshour, Masaru Koido, et al.

• PMID: 37415668
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Prediction Model with HLA-A*33:03 Reveals Number of Days to Develop Liver Cancer from Blood Test

Nao Nishida, Jun Ohashi, Goki Suda, et al.

• PMID: 36902191

Genetic Risk of Primary Aldosteronism and its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies

Tatsuhiko Naito, Kosuke Inoue, Kyuto Sonehara, et al.

• PMID: 36802911
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Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants

Yora Nindita, Masahiro Nakatochi, Rie Ibusuki, et al.

• PMID: 34421081

Investigating the Association between Glycaemic Traits and Colorectal Cancer in the Japanese Population using Mendelian Randomisation

Akiko Hanyuda, Atsushi Goto, Ryoko Katagiri, et al.

• PMID: 37120602

Genome-Wide Association Study of Lung Adenocarcinoma in East Asia and Comparison with a European Population

Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, et al.

• PMID: 37236969
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Mobile Element Variation Contributes to Population-Specific Genome Diversification, Gene Regulation and Disease Risk

Shohei Kojima, Satoshi Koyama, Mirei Ka, et al.

• PMID: 37169872
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Prediction of the Cell-Type-Specific Transcription of Non-Coding RNAs from Genome Sequences Via Machine Learning

Masaru Koido, Chung-Chau Hon, Satoshi Koyama, et al.

• PMID: 36411359

Improved Genetic Prediction of the Risk of Knee Osteoarthritis using the Risk Factor-Based Polygenic Score

Yugo Morita, Yoichiro Kamatani, Hiromu Ito, et al.

• PMID: 37309008

Detection of Trait-Associated Structural Variations using Short-Read Sequencing

Shunichi Kosugi, Yoichiro Kamatani, Katsutoshi Harada, et al.

• PMID: 37388916
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Pan-Cancer and Cross-Population Genome-Wide Association Studies Dissect Shared Genetic Backgrounds Underlying Carcinogenesis

Go Sato, Yuya Shirai, Shinichi Namba, et al.

• PMID: 37340002
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Genome-Wide Association Study Identifies Risk Loci within the Major Histocompatibility Complex Region for Hunner-Type Interstitial Cystitis

Yoshiyuki Akiyama, Kyuto Sonehara, Daichi Maeda, et al.

• PMID: 37467720
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GWAS of Folate Metabolism with Gene-Environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese – the J-MICC Study

Mineko Tsukamoto, Asahi Hishida, Takashi Tamura, et al.

• PMID: 37517992

Genome-Wide Association Studies Categorized by Class of Antihypertensive Drugs Reveal Complex Pathogenesis of Hypertension with Drug Resistance

Keiko Yamazaki, Chikashi Terao, Atsushi Takahashi, et al.

• PMID: 37151119

Hyperfructosemia in Sleep Disordered Breathing: Metabolome Analysis of Nagahama Study

Yoshinari Nakatsuka, Kimihiko Murase, Kazuhiro Sonomura, et al.

• PMID: 37543666

A Whole-Genome Reference Panel of 14,393 Individuals for East Asian Populations Accelerates Discovery of Rare Functional Variants

Jaeyong Choi, Sungjae Kim, Juhyun Kim, et al.

• PMID: 37556544

Contribution of an Asian-Prevalent HLA Haplotype to the Risk of HBV-Related Hepatocellular Carcinoma

Atsushi Kawamura, Koichi Matsuda, Yoshinori Murakami, et al.

• PMID: 37558689

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

Lenka Stolarova, Petra Kleiblova, Petra Zemankova, et al.

• PMID: 37449874

Androgen Receptor Binding Sites Enabling Genetic Prediction of Mortality due to Prostate Cancer in Cancer-Free Subjects

Shuji Ito, Xiaoxi Liu, Yuki Ishikawa, et al.

• PMID: 37612283
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GWAS Meta-Analysis of Over 29,000 People with Epilepsy Identifies 26 Risk Loci and Subtype-Specific Genetic Architecture

International League Against Epilepsy Consortium on Complex Epilepsies.

• PMID: 37653029

Multi-Ancestry Genome-Wide Analysis Identifies Shared Genetic Effects and Common Genetic Variants for Self-Reported Sleep Duration

B. H. Scammell, C. Tchio, Y. Song, et al.

• PMID: 37384397

Boosting the Power of Genome-Wide Association Studies within and Across Ancestries by using Polygenic Scores

Adrian I. Campos, Shinichi Namba, Shu-Chin Lin, et al.

• PMID: 37723263

Combining Asian and European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Racial and Ethnic Populations

Minta Thomas, Yu-Ru Su, Elisabeth A. Rosenthal, et al.

• PMID: 37783704

Natural Selection Signatures in the Hondo and Ryukyu Japanese Subpopulations

Xiaoxi Liu, Masatoshi Matsunami, Momoko Horikoshi, et al.

• PMID: 37903429

Polygenic Prediction Across Populations is Influenced by Ancestry, Genetic Architecture, and Methodology

Ying Wang, Masahiro Kanai, Taotao Tan, et al.

• PMID: 37868036

Identification of Telomere Maintenance Gene Variations Related to Lung Adenocarcinoma Risk by Genome-Wide Association and Whole Genome Sequencing Analyses

Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, et al.

• PMID: 37882647
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A Large-Scale microRNA Transcriptome-Wide Association Study Identifies Two Susceptibility microRNAs, miR-1307-5p and miR-192-3p, for Colorectal Cancer Risk

Zhishan Chen, Weiqiang Lin, Qiuyin Cai, et al.

• PMID: 37903058

Extracting Immunological and Clinical Heterogeneity Across Autoimmune Rheumatic Diseases by Cohort-Wide Immunophenotyping

Hiroaki Tanaka, Yukinori Okada, Shingo Nakayamada, et al.

• PMID: 37903543
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Characterizing Prostate Cancer Risk through Multi-Ancestry Genome-Wide Discovery of 187 Novel Risk Variants

Anqi Wang, Jiayi Shen, Alex A. Rodriguez, et al.

• PMID: 37945903

East Asian-Specific and Cross-Ancestry Genome-Wide Meta-Analyses Provide Mechanistic Insights into Peptic Ulcer Disease

Yunye He, Masaru Koido, Yoichi Sutoh, et al.

• PMID: 38036781
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