GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Polygenic risk score and lung adenocarcinoma risk among never-smokers by EGFR mutation status-a brief report

Genetic analysis of myeloid neoplasms with der(1;7)(q10;p10)

Cancer and disease profiles for PTEN pathogenic variants in Japanese population

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Identification of an novel genetic variant associated with osteoporosis: insights from the Taiwan Biobank Study

Genetic variants for head size share genes and pathways with cancer

A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk

Protocol for genome-wide association study of human blood metabolites

KEAP1–NRF2 system regulates age-related spermatogenesis dysfunction

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults

Large-scale cross-trait genetic analysis highlights shared genetic backgrounds of autoimmune diseases

Artificial intelligence in medical genomics

Genotype imputation methods for whole and complex genomic regions utilizing deep learning technology

Statistically and functionally fine-mapped blood eQTLs and pQTLs from 1,405 humans reveal distinct regulation patterns and disease relevance

Genomic variants associated with age at diagnosis of childhood-onset type 1 diabetes

A genome-wide association analysis reveals new pathogenic pathways in gout

Polygenic risk score for blood pressure and lifestyle factors with overall and CVD mortality: a prospective cohort study in a Japanese population

Poor accuracy and sustainability of the first-step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencing

Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

Body mass index stratification optimizes polygenic prediction of type 2 diabetes in cross-biobank analyses

RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial Infarction

Genetic Risk, Healthy Lifestyle Adherence, and Risk of Developing Diabetes in the Japanese Population

Genetic Risk Stratification of Primary Open-Angle Glaucoma in Japanese Individuals

Genome-Wide Association Study with Three Control Cohorts of Japanese Patients with Esotropia and Exotropia of Comitant Strabismus and Idiopathic Superior Oblique Muscle Palsy

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

Genetic legacy of ancient hunter-gatherer Jomon in Japanese populations

Genome-wide association study on meningioma risk in Japan: a multicenter prospective study

Common and rare genetic variants predisposing females to unexplained recurrent pregnancy loss

Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues

Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease

Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome‐Wide Association and Mendelian Randomization Study

Machine learning reveals heterogeneous associations between environmental factors and cardiometabolic diseases across polygenic risk scores

Genome-wide association studies for pelvic organ prolapse in the Japanese population

Population-specific putative causal variants shape quantitative traits

Inconsistent embryo selection across polygenic score methods